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From in vivo to in vitro study of cell intercalation – Inter-s-cal
possibility to explant and study this tissue in vitro to perform an in-depth investigation of the cellular
Understanding Keloid Disorders: A multi-scale in vitro/in vivo/in silico approach towards digital twins of skin organoids on the chip – S-Keloid
in vitro cell models cultured under mechanical and biological stresses in order to mimic in vivo situation
Bioinspired interface engineering of DGL-based hydrogel with high mechanical performance and bioactive properties for in vitro biomaterial platform – DENDRICELLPLATFORM
several protocols inducing ex vivo stem cell differentiation before in vivo transplantation. But to obtain [...] tissues or organoids, a main drawback is the ex vivo production of clinically relevant quantities of [...] culturing adherent cells which best reproduce in vivo conditions. Natural or synthetic polymers have long
In vitro maintenance of FOXP3+Treg cells phenotype, epigenetics and function stability in humans – MAINTREG
specific epigenetics and suppressive function in vitro and in vivo. By next gen methods combining surface markers [...] therapy trial in liver and kidney transplantion, in vitro developping CAR-Treg cells and thymic Treg cells
Prion Domains in Plant Environmental Response – PROSPERO
LLPS in vitro and/or in vivo. Using an integrated in vitro, structural, modeling and in vivo approach [...] determined. These in vitro and modeling results will be correlated with in vivo studies in transient [...] mutants with altered LLPS. Through iterative in vitro characterization including studies by small angle
Metal-Azadipy multimodal Probes (MAP): find your way in vivo – MAP
regarded only as an in vitro tool, has recently gained an increasing interest for in vivo applications, especially [...] infrared-emitting fluorophores – preferable for in vivo imaging – are long to synthesize, difficult to [...] urgent need for new near-infrared fluorophores for in vivo optical imaging, especially for fluorescence-guided
in vitro reconstitution of the minimal flippase-operated phospholipid transport machinery – FLIPPER
to dissect this regulatory mechanism, using in vitro reconstitution of the lipid transport machinery [...] provide a mechanistic basis for Drs2 activation in vivo and reveal new functions for understudied small
Porous hydrogel under perfusion: modeling and optimization of an in vitro model of bone defect reconstruction – HydrOs
for promoting osteoinduction will be assessed in vivo.
Neurotransmitter glycation products: Interrelation between ADTIQ and the Park7/DJ-1 repair system – ADTIQ-PARK
formation in vitro and accumulation in vivo, and can ADTIQ control DJ-1 activity in vitro and in vivo? • Does [...] in PD pathogenesis. Quite recent preliminary in vitro data from our team suggests indeed that ADTIQ inhibits [...] to aging and to PD-related neurodegeneration in vivo? To this end, we would like to combine the c
Structure diversity, functionality and modulation of milk oligosaccharides in monogastric livestock species: towards optimal development of rabbit and pig holobionts – HoloOLIGO
validate results in vivo. Finally, we will evaluate, via in silico analyses (pig) and in vivo (rabbit), the [...] of milk oligosaccharides, we will undertake in vitro functional analyses in both species on commensal